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Particles in parenteral drug products continue to be an important concern. At the April-2017 AAPS Workshop Challenges and Patient Impact of Particles in Biologics, Fran DeGrazio, VP of Scientific Affairs and Technical Services, spoke on the topic: Unique Considerations for Testing and Understanding Particle Loads for Primary Packaging Components.
The presentation addressed three major issues: source, control and measurement. Particles represent a very serious risk to patient safety – especially those from external sources, where bioburden is uncontrolled. Sources of particles are many: materials, equipment, processes, people, methods, and release/receipt. The best way to understand the sources, and be in the best position to exercise control over these sources, is through an Ishakawa cause-and-effect analysis – identifying and understanding the influence of all possible factors. Critical as well is the measurement of particles: number, size and composition. However, the challenge is the execution of measurement – which requires considerable insight and laboratory expertise. Identification requires different methods. And like identifying sources of particles, a cause-and-effect analysis must be done to understand factors (e.g., equipment, preparation) that affect limits of uncertainty in measurement.
Particles in parenteral drug products will always pose a risk to patient safety. Better measurement ultimately leads to better understanding of the source, and a better ability to control. West’s aim is to be at the forefront in developing more effective methods to measure particles, with the goal that is always in mind – patient safety. To read Fran DeGrazio's full presentation, visit the Knowledge Center.
Prefillable syringes have become an increasingly important option in the packaging and delivery of injectable drug products. The prefillable syringe serves two major purposes for the administration of a drug. The first is as primary packaging by assuring that there is no adverse effect on the identity, strength, quality, purity or potency of the drug over its shelf life. Second, a prefillable syringe is a delivery system designed to administer the appropriate amount of the drug to the patient reliably
Come one, come all to the 2014 West without Borders campaign! From preliminary planning to the final one-ring circus, the 2014 West without Borders campaign in Kinston, N.C., was a whole lot of clowning around in the name of a good cause. This year, Kinston team members supported three charities: Relay for Life Kids’ Walk, Kid’s Cafe and Shriners’ Hospital for Children’s Transportation Fund.
We are pleased to present the newly designed Westpharma.com. Our passion for customers goes beyond just the products and services we offer. Our website redesign brings to life our 90+ years of expertise and focuses on simplifying our customers journey to help them find the right solutions for their drug packaging and delivery challenges. Take a fresh look at how our solutions can help you.
Employees from The Tech Group’s Phoenix, Rockford, Scottsdale and Tempe West facilities raised more than $72,000 for Upward Children and Families as part of the 2013 West without Borders fundraising campaign.
We are happy to announce that West received the 2015 India Pharma Award for Outstanding Primary Packaging for Injectables for our high-quality NovaPure® components. The award was presented to West during the CPhI India Pre-Connect Congress.
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