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Controlling Ice Nucleation During the Freezing Step of Lyophilization - Lyophilization Technologies for Controlled Nucleation
This article, written by Adeline Siew, is published on Pharmaceutical Technology, 37 (5) (May 2, 2013)
This article discusses the issues that can result from uneven ice nucleation across multiple vials in a lyophilization chamber, and temperature variation strategies that can address them.
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