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By Mary Tan

January 25, 2021

One of the main risks associated with drug delivery via vial containment systems is particles that can result from fragmentation and coring of rubber stoppers subjected to needle or spike punctures. This risk can be mitigated by using prefilled syringe systems, whereby the drug dosage has been filled into the syringe by the drug manufacturer. The drug dosage is then administered by subcutaneous or intramuscular injection. A prefilled syringe system generates fewer particles during drug administration, as compared to a vial containment system. Furthermore, this form of drug delivery system ensures efficiency and greater convenience.

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By Global Communications

June 12, 2014

In recent seminars in Hyderabad and Ahmedabad, India, West’s Tibor Hlobik discussed the challenges faced by injectable drug manufacturers to minimize risk, accelerate product development, ensure patient safety and improve ease of administration. Similar seminars were held in China and Korea.

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By Tibor Hlobik

November 25, 2013

As biologics and other injectable drug products gain market share, greater scrutiny is being paid to the interaction between the drug product and its container closure system, including stability during shelf-life and particulate burden, among other critical quality attributes. Over the last several years, drug product recalls have increased due to quality issues, including fundamental weaknesses in primary glass containers that have resulted in problems such as breakage or delamination. Additionally, as more attention is paid to the integration of primary drug containers with devices to form combination products, finding solutions to these problems has taken on an increased urgency in order to protect patients by assuring the integrity and proper delivery of drug products.

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By Tibor Hlobik

November 20, 2013

Component processing is a source of risk and variability, especially for loose particulate and silicone oil that can compromise quality, putting patients at risk. To simplify drug development and streamline manufacturing, pharmaceutical companies can select cartridge plungers and lined seals in a ready-to-use format.

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By Global Communications

October 07, 2013

Several of West’s experts will be featured speakers at The Universe of Prefilled Syringes and Injection Devices organized by 2013 PDA Europe, which will be held November 5-6, 2013, in Basel, Switzerland. West’s representatives will report on the latest trends in the world of prefilled syringes and innovations in the field of self-injection devices.

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By Whitney Winters

June 06, 2013

For many pharmaceutical manufacturers, commercial filling lines are simply a part of the manufacturing process. But when a drug is still in development or requires prescreen stability testing for new primary container selection , small-quantity filling can be difficult. To send such quantities to a contract manufacturer or commercial lines, such as isolator or RABs, can be expensive and time consuming.