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By Patrick Curran and Vinod Vilivalam

May 08, 2013

Patrick Curran1, Vinod Vilivalam1, Suzanne Kuiper2 and Derek Duncan2
1West Pharmaceutical Services, Inc. and 2Lighthouse Instruments B.V.

An increasing number of pharmaceuticals including vaccines, stem cells and proteins require cold storage to maintain efficacy prior to use. However, the ability to maintain container closure integrity (CCI) during cold storage is not completely understood.