The drug and packaging industries have always been extremely conscientious to ensure that anything added to a delivery device to improve performance (e.g., silicone oil used to coat the inner surface of a syringe barrel), does not affect a drug’s efficacy or safety. But what about the converse? How do we make sure that the drug, or more specifically its added excipients, does not affect the delivery system’s performance? The term excipient refers to any member of a broad group of surfactants, preservatives, tonicity agents, and buffers which formulation scientists take great care to balance in order to provide the drug, such as a therapeutic protein, in its most effective and deliverable state.

Liang Fang Ph.D.

November 11, 2021

A point to consider in piercing a rubber stopper with a needle is formation of cores and fragments. Their presence in a drug is a critical concern. Both are considered particulate matter.

West

November 03, 2021

West celebrated 40 years of successful operations in Kovin, Serbia during the month of October 2021. The West Kovin manufacturing facility specializes in the manufacturing of stoppers and plungers for disposable syringes.

Gillian Power

October 28, 2021