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By West Technical Customer Support

June 23, 2014

One of the challenges a drug manufacturer faces is controlling the drug product at the point-of-use in a hospital or clinical environment.  Often the method of vial access is variable, leading to an increased risk of harmful patient outcomes such as stopper cores or fragments entering into the drug product, which can contribute to cardiovascular events. There are a number of causes that contribute to stopper coring and fragmentation in the field that depend primarily on the technique of the practitioner and the properties of the elastomeric closure.