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In 2012, the pharmaceutical industry will face many challenges, not the least of which will be the need to adjust research and development and business models to respond to the growing importance of specialty pharmaceuticals. Such products include sensitive biopharmaceuticals and the growth of biosimilars. Efficiency in manufacturing and the ability to meet critical compliance standards are a must to compete and meet today’s challenges.
Effective packaging selection early in the development process can be key for sterile pharmaceutical manufacturers. Early partnerships help pharmaceutical manufacturers select consistent components that can be used throughout the drug product’s lifecycle and potentially mitigate risk associated with issues such as particles, which can be impacted by an elastomeric component or by the container holding the drug. An example of the latter is glass delamination of vials, which has driven many market recalls in the recent past. Additionally, as delivery systems are utilized to a greater extent with many specialty pharmaceuticals, the ability to assure the packaging and delivery system work together effectively minimizes risk and total cost.
Overall, early partnerships, consistent components and unique delivery systems can help to lower a drug manufacturer’s total costs and mitigate risk when moving a drug to market.
West offers a variety of solutions for its customers. To learn more, visit www.westpharma.com.
<p><strong>Applying metrology–the science of measurement–to the art of medical device design.</strong></p><strong></strong><p><strong></strong><em>The Tech Group’s Keith Calvert recently contributed a three-part blog on metrology to Medical Design Technology. The following is from Part 1.</em></p>
<p>Last month, I gave an overview of how West’s IT strategy supports the “One West – Customer First” business strategy through three major investment areas:</p><ul><li>Customer Relationship Management, or CRM</li><li> Supply Chain Management, or SCM</li><li> Business Analytics and Dashboards</li></ul>
<em>This is the second in a two part series dedicated to the origins and attributes of the Daikyo Crystal Zenith® polymer </em>
On Saturday, July 13, a team of West colleagues and family members participated in the 2013 Merrell Down & Dirty National Mud and Obstacle Series in Philadelphia, Pa. The run is a 10k with a series of obstacles including: <a href="http://www.downanddirtymudrun.com/obstacles/straw-bales-slippery-mountain/"><span style="color: #0000ff; text-decoration: underline;">slippery mountain and inflatable</span></a>, <a href="http://www.downanddirtymudrun.com/obstacles/mud-pit-water-crossings/"><span style="color: #0000ff; text-decoration: underline;">mud pit and water crossings</span></a>, and <a href="http://www.downanddirtymudrun.com/obstacles/marine-hurdles-cargo-net-climb/"><span style="color: #0000ff; text-decoration: underline;">Marine hurdles and cargo net climb</span></a>.
Particles in parenteral drug products are a serious concern; they can cause issues such as product recalls, or worse, immunogenic responses. Sources of particles are varied; they can be from aggregates of biologic API’s, excipient contaminants, components, or silicone oil used to promote syringe function. With emphasis on safe and efficient delivery of drug products, West is focused on strategies to both measure particles, and mitigate their presence.
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