Surface Properties and Enhancements
Surfaces of a drug product container/delivery systems are often modified to enhance performance by: (a) reducing interaction with drug product, (b) retarding migration of leachables into drug product, and (c) facilitating delivery (e.g., easier plunger movement). Typically modification is a fluoropolymer (West FluroTec® branded products) or polysiloxane (B2-Coating technology) coating. This section presents papers on surface modification technology and resultant effects.
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The differences between B2 and FluroTec® and their applications are discussed.
Study done to compare extractables between FluroTec and non-laminated stoppers
FluroTec® technology is licensed from Daikyo Seiko, Ltd.
B2-Coating technology is licensed from Daikyo Seiko, Ltd.