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Cartridge-based administration using injection device systems has dominated the insulin market for many years. In 2011, the insulin market for cartridge-based container closure systems was at an estimated 1 billion units. Additional applications for cartridge-based container systems include dental, at more than 450 million units per year, and therapies such as human growth hormone, interferon and epinephrine. In fact, thanks to lower production costs when compared to vial and syringe systems, cartridge-based delivery has found a widespread and growing market.
As the healthcare market continues to evolve and administration in the home care setting increases, cartridge-based delivery has made inroads into a variety of markets. Today, systems are in use or are under consideration for use with such therapeutic categories as anemia, rheumatoid arthritis, dermatology, oncology and hepatitis. In addition, insulin use is increasing due to the growth in population and higher demand in emerging countries, so the diabetes care market is evolving to provide more accurate and reproducible dosing. Insulin pen injectors, which commonly employ a 3.0mL cartridge, provide convenience and ease of use to patients, which may in turn help to improve patient compliance.
As the global market moves toward home-based care and multi-dose delivery systems for select therapeutic categories, pharmaceutical manufacturers are now seeking sterile components, including cartridges, plungers and other high-quality components, that are capable of offering ready-to-use quality and high functional performance in a variety of delivery systems and devices. Such quality is essential to the functionality, safety and efficacy of pens, injection devices and cartridge-based delivery systems.
West offers high-quality, ready-to-use cartridge components. Our industry-proven Westar® component processing reduces the risk of variability and its potential effects on drug quality, safety and efficacy.
Elemental impurities, such as arsenic, cadmium, lead and mercury are ubiquitous in nature. They are also toxic to humans and animals at certain levels. Because these elements are often part of mined minerals used in the manufacture of drug products and/or drug containment systems, they can have an impact on the quality of a drug. <br />
Join our subject matter experts in Boston for the 2013 Educational Series, “Supplying Safe Medicines to Patients: Considerations for Container Closure and Delivery Systems.”
On a cold, early morning in the first week of March, hope arrived at Community Volunteers in Medicine (CVIM) in West Chester, Pennsylvania in the shape of a small, frozen box. After many months of dedicated work, CVIM became an official vaccination site in Chester County, and could now work to vaccinate at-risk individuals in our shared community.
In the next blog of our series on West’s 2017 Corporate Responsibility Report, we are focusing on Compliance and Ethics. As a company that operates in a highly regulated industry to serve billions of patients around the world, it is imperative that West conducts its business in an ethical manner – not because we have to, but because it’s the right thing to do. Read on to learn more about compliance and ethics at West as published in the 2017 Corporate Responsibility Report. <br />
The FDA’s Center for Devices and Radiological Health (CDRH) released four final guidance documents on Thursday, Sept. 12, which provides the FDA’s current thinking on the Special 510(K) program, the Abbreviated 510(K) program, how to format Traditional and Abbreviated 510(K)s and the new Refuse to Accept policy for 510(K).
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