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In the first of three installments of our video tour of our Scottsdale, AZ, plant, Jeff Kyle, Sr. Director Operations and Supply Chain, speaks to what gets him excited about working at West: The knowledge that they are helping to improve the lives of patients by creating innovative drug packaging and delivery systems.
While compliance and standards are a very important part of the Scottsdale manufacturing philosophy, Jason Choi, Project Engineer, says—above all else—West employees keep in mind the patients who will eventually use the components and systems they’re making.
Creating a positive environment of like-minded employees starts with hiring the right people. At Scottsdale, employees dedicate themselves to serving the customer – and the patients impacted by their pharmaceutical products – to ensure products get out the door in time and are safely and effectively delivered to the patients.
Another aspect of that work culture, Kyle says, is the supportive environment in which employees work together, from top management to the technicians. It starts with mutual respect for everyone’s ideas in meetings – fostering a climate in which everyone feels, “we’re in it together” and a sense of ownership of the products they’re making as a team.
West strives to be the world leader in the integrated containment and delivery of injectable medicines. The achievement of this goal relies on many factors, including a heightened awareness of industry and regulatory trends. By being able to anticipate these trends, West is better able to support its customers with the knowledge and services needed to ensure that drug products reach market on schedule.
The global pen injector and auto-injector markets have witnessed significant growth due to the increasing demand for self-administration of injectable drugs. Pen injectors and auto-injectors provide a user-friendly and convenient solution for patients to administer medications, contributing to improved patient compliance and overall healthcare outcomes. There are well established traditional market segments that use cartridge-based delivery systems, including dental local anesthesia and diabetes care, as well as human growth hormone and allergy therapies. However, there have been significant developments in the incorporation of cartridges in auto-injectors as supposed to the traditional syringe designs.
The pharmaceutical industry’s focus on extractables and leachables from packaging/delivery systems began during the mid-1990’s. Today’s regulatory agencies are more educated about the process, and drug product formulations have become more complex, which makes the need for robust extractables and leachables programs more critical than ever. In fact, failure to properly evaluate extractables and leachables has had a negative impact on many pharmaceutical companies, e.g., late-stage stability failures, submission delays, and recalls. To avoid this, the first question to ask is – “where do I start?”
Recently, 16 of the interns from the 2019 West Ambassador Internship Program visited two West sites in Jersey Shore and Williamsport, Pennsylvania. As interns from the corporate headquarters, the tours of the two local manufacturing locations offered a unique perspective to contrast the corporate experience. During the Jersey Shore and Williamsport tours, the interns were given a different experience to visualize the making of the product itself.
“Choosing the Right Components for Container Closure Systems,” the second part of our “How to Qualify Container Closure Systems” series, was recently published in the International Journal of Pharmaceutical Compounding. The article addresses ways in which packaging component selection is critical to ensuring that the closure container system will protect and maintain compounded drug quality.<sup>1</sup>