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At the recent 2018 PDA Parenteral Packaging in Rome, Dr. Qingyu Zeng, Principal Scientist in the Scientific Insights Lab in Scientific Affairs & Technical Services, gave a presentation entitled Critical Time- & Temperature- Dependent Container Closure Integrity (CCI) Through the Sealed Drug Product Life Cycle. This presentation gave an update on research that aims to provide fresh insights to the parenteral packaging industry.
By employing both testing evaluation and modeling calculations, research results demonstrate that container closure sealing performance has a critical nature of both time- and temperature-dependency. Discussion included how to develop a systematic approach to proactively and practically consider: design, set up, control, and management of stopper sealing performance. In addition, cosmetic vial assembly acceptance through proper considerations in container closure system (CCS) and capping processes was discussed. These techniques are intended for the purpose of ensuring sufficient sealing performance throughout the entire sealed product life cycle.
Small things sometimes come in large packages. When it comes to pharmaceutical components, small items like stoppers and plungers are often sold in quantities large enough to supply drug products to the world. But sometimes, and in particular during the early stages of drug development, large quantities are just too much of a good thing.
For the first time in history, there are five generations in the workforce: Traditionalists, Baby Boomers, Gen X, Gen Y (also referred to as Millennials) and Gen Z. Ranging from pre-1946 to after 1997, these groups represent a wide range of ages where employees will inherently have different workstyles and views, which can pose some interesting challenges. Unfortunately, misunderstandings and perceptions can overshadow the strengths that each generation brings to the workforce.
<p>By Katrina Firlik, MD<br>Chief Medical Officer<br>HealthPrize Technologies</p><p>Although modern pharmaceuticals and advanced drug delivery systems save and improve the lives of millions of people around the world, there are countless others whose lives are not saved or improved—because they don’t take the medication at all, or often enough. Former Surgeon General C. Everett Koop summed it up best: “Drugs don’t work in patients who don’t take them.”</p>
Seeking technical support? Need a little information about fill-finish manufacturing technology? How about advice from the experts on extractables and leachables? These answers, and more, are available in the new West Knowledge Center.
West Pharmaceutical Services team members performed especially well this year for the Janssen Supply Chain Global Procurement Organization (a part of the Johnson & Johnson group of companies), which recently presented the team with the bronze Supplier Award. The award was presented during a ceremony at the J&J facility in Turnhout, Belgium, on May 7.
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