We apologize your item could not be found. Not all items are listed on our website. Please contact your account manager for details regarding your searched item.
Material number (eg: xxxxxxxxxxx) no space or hyphen needed.
No Results Found
Prefillable syringes have become an increasingly important option in the packaging and delivery of injectable drug products. The prefillable syringe serves two major purposes for the administration of a drug. The first is as primary packaging by assuring that there is no adverse effect on the identity, strength, quality, purity or potency of the drug over its shelf life. Second, a prefillable syringe is a delivery system designed to administer the appropriate amount of the drug to the patient reliably
There are two major types of prefillable syringe systems available:
Traditionally, a prefillable syringe barrel has been made from glass tubing. These glass tubes are transformed by heat into the barrel that is used to hold the drug product. Syringe manufacturers typically form and process the glass and purchase the complementing elastomeric components (e.g., plungers, tip caps, needle shields) that complete the primary package from an elastomeric closure manufacturer.
The benefits of glass systems include:
There are, however, drawbacks:
Plastic-based syringe systems are gaining acceptance because of their benefits compared to glass systems. The Japanese market, which is well known for its high quality, has transitioned over 50% of its syringes to plastic because of its superior performance.
The most widely used prefillable plastic syringe systems are manufactured from cyclopolyolefin (COP) resin. These systems are manufactured to very high quality standards and to tight dimensional tolerances. As there are many types of plastics, it is imperative to understand the unique characteristics of the plastic syringe system being evaluated because the package choice is critical in ensuring the long-term success of a pharmaceutical or biopharmaceutical drug product.
The benefits of plastic-based systems include:
To learn more about prefillable syringe systems, click here.
West's contract manufacturing team has once again reached a record level of support for Temple Street Children’s Hospital and recently presented a check for €18,000 that was raised by employees in 2015.
The West without Borders fundraising initiative had a terrific year in 2011 and as we kick off the 2012 campaign, we can look forward to another great year of aiding charities in the communities where West employees live and work. In 2011, West employees contributed more than $210,000 to aid local charities.
A parenteral drug product contaminated by particles is a potential health threat. In the bloodstream, particles can cause serious issues, such as capillary occlusion and immunogenic responses. In most cases, the observation of particles in a drug product leads to a recall.
Polymeric container systems are not new to the pharmaceutical industry, and their benefits in terms of break resistance, cosmetic quality and dimensional precision have been recognized by many companies around the world who have chosen to use a polymer vial or syringe.
The glass transition temperature (T<sub>g</sub>) is the temperature at which a material loses its viscoelastic properties. It is also indicative of the lowest temperature at which the polymer system will retain its functionality.
English
Chinese
