Previous Blogs

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By Prabhaharan Sankaran

May 18, 2021

Globally, the market for biologic drugs is growing significantly, due to their proven ability to treat major chronic diseases, in particular those found among an increasingly aging population. Cartridge systems are very important in delivering these biologic drugs; they can be used in autoinjectors, pen injectors, and wearable devices. Since biologics drugs are very sensitive, they require highest-quality cartridge components.

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By Erin O'Brien

November 27, 2019

West is excited to announce an addition to its NovaPure® product line — NovaPure 3mL Cartridge components, which include plunger and seal components specifically designed to ensure consistency of delivery for higher-volume injectable drug delivery systems. The components were designed to address specific issues and challenges the pharmaceutical industry faces in bringing innovative injectable drug products to market.

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By Amy Kim

October 18, 2019

With the May 21, 2019 meeting to review the FDA draft guidance governing 503B compounding pharmacies, it has become evident that sterility of drugs produced at such facilities is a major focus of the U.S. Food and Drug Administration (FDA).1 The meeting discussed the importance of qualifying container closure systems and was aimed at providing more context on what compounding pharmacies need to do.

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By Christa Jansen-Otten, Director, Product Management

February 06, 2017

Modern biopharmaceutical drug molecules are often complex protein structures that need to maintain the molecular structure in order to convey full potency. With biologics, any alteration of the 3-D structure could lead to loss of activity or even to immunogenic reactions in the patient. Proteins can be disrupted by interactions with the container closure or with leachables. West FluroTec® lamination was chosen for NovaPure® plungers to reduce the interaction between the drug product and elastomer material. This includes less adsorption to the plunger surface as well as reduction of the leachables profile of the plunger, helping to maintain the stability of complex molecules.

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By Jeanette Hampe

August 13, 2015

Because differences exist between regulatory agencies from region to region, West regulatory affairs continually stays informed of new developments and changes in order to provide customers with accurate regulatory support regarding packaging requirements.

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By Jessica Tiegs

December 03, 2014

As regulatory expectations increase, drug product manufacturers face increased pressure to produce products free of defects and minimize rejects of finished drug products. Particulate matter in finished pharmaceuticals can come from a number of sources, including the ingredients in the drug product, manufacturing equipment or the container closure system.