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When left untreated, diabetes eventually can lead to a variety of issues for patients, including complications such as stroke, blindness and heart and/or kidney disease. In addition, adherence to painful or inconvenient injection treatments can be difficult for patients, with as many at 57% of Type 1 and Type 2 diabetes patients admitting to intentionally skipping injections.1
New research into biologics has helped to develop options for a number of chronic conditions, including diabetes. High-quality containment and delivery systems may help make diabetes treatment better for patients. In addition, for pharmaceutical manufacturers, high-quality products can provide tighter break-loose and extrusion forces, and improve manufacturability.
Drug companies should seek out packaging and delivery development partners with the following qualities:
Adoption of QbD Design Principles
QbD principles help to ensure that containment and delivery systems are designed with the patient in mind. Driven and supported by regulatory guidance, QbD delivers an improved, data-driven output that provides manufacturers with superior product and process understanding that minimizes risk, emphasizes patient-critical quality requirements and maximizes drug product effectiveness.
A Patient-Centric Approach to Delivery
Injections can be painful. Human factors testing of delivery systems and devices can help to ensure that issues such as delivery time, dose volume, and even the look and feel of the device or system are beneficial to the patient. Drugs won’t work in patients who don’t use them, so making drug delivery an easy, consistent, and discreet option will help patients stick to their therapeutic regimens.
An Eye on Connected Health
Smartphones are everywhere. Mobile devices and tablets are in constant use. So why not make them work for patients? By connecting dose delivery to a software as aservice platform that tracks and rewards adherence, diabetes patients may improve their overall health. Unique gamification technologies can reward and educate patients, while incentivizing them to continue their treatment and encouraging adherence.
With the right focus on quality systems, patient-centric delivery systems, and unique connectivity to enhance adherence, pharmaceutical manufacturers can provide patients with powerful systems that may help resolve the more challenging problems associated with self-care for chronic conditions. By selecting the right partner, pharmaceutical companies will not only provide a unique product to patients, but also help them care for their condition.
Lyophilization removes water from a drug product through three phases: freezing, primary drying or sublimation, and secondary drying or desorption. To begin the process, the drug product is frozen and then placed under a vacuum, which allows the ice to change from solid to vapor without passing through a liquid phase.
<span style="color: black;">West is <a href="https://www.youtube.com/watch?v=42PhOvTdfRg"><span style="color: #0000ff; text-decoration: underline;">on the road</span></a> again, traveling more than 1,000 miles from our Jersey Shore, PA, manufacturing facility—where we visited during our first installment of <a href="https://westpharma.wordpress.com/2015/06/01/west-kicks-off-west-on-the-road/"><span style="color: #0000ff; text-decoration: underline;">West On The Road</span></a> —to the sunshine state, where we’ll be touring our state-of-the-art Clearwater plant.</span>
Glucose monitoring, or measuring the amount of sugar in the blood, is a vital part of everyday care for those suffering from diabetes. Traditional tests require patients to prick their fingers and place a drop of blood on a test strip. The strip is then placed in a glucose meter that reports the results to the patient. While this test is very accurate, it offers a reading for only a single point in time. For patients to get a range of their blood glucose levels, more frequent data is needed at a variety of different times.
<p>West is thrilled to announce that Lisa Bakazias, VP, Operations, Manufacturing Strategy, was recently named as our 2018 HBA Luminary.</p>
For the second consecutive year since its inception, a total of 91 West employees rose to the challenge and participated in the actimonda Business Run on May 15 in Aachen, Germany.
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