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As drug manufacturers aim for higher safety standards and enhanced patient care, controlling the drug product at the point-of-use in a hospital or clinical environment remains a significant challenge. The method of vial access often varies, increasing the risk of adverse patient outcomes, such as stopper cores or fragments entering the drug product. If injected, these fragments can lead to cardiovascular events and other complications. Several factors contribute to stopper coring and fragmentation in the field, primarily influenced by the technique of the practitioner and the properties of the elastomeric closure.

Sanjeev Seenath

July 09, 2025

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Previous Blogs

Prevention is Better than a Cure: Avoid the Costly Fall Out from Radiopharmaceutical Spillage

By Victoria Morgan

September 04, 2018

As global healthcare systems become more heavily reliant on radiopharmaceuticals for diagnostics and treatment, ensuring that the radioactive drug is safely contained for the duration of its shelf life has never been more vital.

West to Moderate Prefillable Glass Syringe Symposium

By Global Communications

April 30, 2013

Christa Jansen-Otten and Dr. Heike Kofler will moderate the ”Prefillable Glass Syringe and the Appropriate Pharmaceutical Rubber Components: Processing, Packaging, Innovations,” at the 53° SIMPOSIO AFI in Rimini, Italy, on June 12-14, 2013.

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Films and Coatings

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Prefillable Systems

Self Injection Devices

Vial Containment Solutions

Washing and Sterilization

Reconstitution and Transfer Devices

Select a sub-category to view results

Analytical Lab Services

Contract Manufacturing

Fill-Finish

Regulatory Support

Select a sub-category to view results

Cell and Gene Therapy Packaging

Drug Development Process

Regulatory Challenges

Transitioning to Combination Products

Select a sub-category to view results

Corporate Development

ESG/Sustainability

One West Team (Employee Culture)

Our Culture of Giving (Philanthropy)

Research and Development