<p>The needle of a pre-filled syringe is extremely important. From manufacture, through packaging/transportation, to patient delivery &ndash; if the needle is not protected, the drug product cannot be delivered effectively.&nbsp; To protect needles to ensure patient safety, West has developed <a href="~/link.aspx?_id=F855C01F45BB4381A332095C208010F4&amp;_z=z">Rigid Needle Shields </a>(RNS) in two sizes: 1/2&rdquo; for subcutaneous injections (e.g., heparins) and 5/8&rdquo; for intramuscular injections (e.g., vaccines). RNS consist of a two-part system &ndash; a soft rubber inner shell and a perforated, hard polypropylene outer shell. This system maintains container closure integrity (CCI) for both an ISO 11040 glass syringe with staked needle, and a polymer-based syringe (e.g., <a href="~/link.aspx?_id=E331B37C8C774886B3202AC13D84FCCA&amp;_z=z">Daikyo Crystal Zenith&reg; insert needle syringe</a>).</p>