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Mitigating the risk of coring and fragmentation during needle insertion for drug administration

Describes various factors affecting fragmentation when piercing a stopper.

The correct handling during piercing of the rubber stopper is essential to prevent fragmentation of the elastomeric closure. The following factors will influence performance during a puncture...

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Mitigating the risk of coring and fragmentation during needle insertion for drug administration

Describes various factors affecting fragmentation when piercing a stopper.

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