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The future is now for parenteral pharmaceutical and biopharmaceutical sterile production. Traditional high-volume automated aseptic filling suites are maintained by contract filling services. But what’s emerging? Parenteral pharmaceutical and biopharmaceutical industries have transitioned to fully enclosed, isolator/restricted access barrier (RAB) systems. These small, efficient systems offer cost savings and can reduce the potential for particulate and microbial ingress during aseptic fill/finish manufacturing by eliminating direct human contact in the filling environment.
These systems often necessitate that supplies be introduced via a rapid transfer port in the isolator/RAB systems without breaking the system’s sterility. Port bags are a must for these sterile systems. The beta port on the port bag interlocks and docks to the alpha port on the isolator/RAB systems.
Port bags are available to transfer sterile packaging components and sterile items into the restricted sterile systems. The port bags, which are available in various sizes, meet steam or gamma sterilization requirements and are constructed with the necessary ports to dock to rapid transfer systems. For further information on West’s port bag packaging systems to overcome the obstacles of introducing sterile packaging components into isolator/RAB systems, contact your account manager today.
For more information read:
“RABS and Advanced Aseptic Processing,” May 1, 2006, James P. Agalloco, James E. Akers, Pharmaceutical Technology
“Restricted Access Barriers – RABS definitions and performance,” Bioquell UK Ltd, Pharmaceutical International
Take an in-depth look at the science behind containment & delivery of injectable medicines in the West Knowledge Center.