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Part I This is a first in a two part series dedicated to the origins and attributes of the Daikyo Crystal Zenith® Polymer In the early 1990s, Masamichi Sudo, founder and past president of Daikyo Seiko, Ltd., first developed the Daikyo Crystal Zenith polymer. This custom formulated cyclic olefenic polymer, available today in the Daikyo Crystal Zenith (CZ) portfolio of products offered by West, represents his lifelong ambition to improve all aspects of parenteral packaging and commitment to delivering the most precise formulation to the marketplace.
Mr. Sudo started his endeavor by creating reliable elastomeric closure solutions like B-2 lubricious coating and Flurotec® barrier film, a fluropolymer film lamination to protect both elastomer and drug product from each other. Enormously successful, these technologies led the way for Mr. Sudo to turn his attention to the nagging problems related to him by clients who were dissatisfied with glass and other vessel materials such as polypropylene and polyethylene.
Working with one of the world leading polymer suppliers, Mr. Sudo rejected formulation after formulation in a demanding search for the perfect pharmaceutical container. He sought after a material which would safely contain his clients life-saving drug products without changing it in any way. In addition, he demanded robustness so that physical damage would be a thing of the past. Just like the glass vial, rubber stopper and metal seal system replaced the glass ampoule on a grand scale, he hoped that the new material would supplant these legacy materials to the benefit of patients around the world. Finally, after years of empirical study of various polymer recipes, Mr. Sudo was satisfied with what we now know as the Daikyo Crystal Zenith polymer, or simply CZ.
Check out the West blog next week to learn more about CZ’s properties and the ways in which CZ compares to glass.
I retired from West in 2017. My West experience over my 34 years of being a team member left me with many fond memories and relationships that I still have today. West’s motto of integrity, strong work ethic and philanthropy aligned well for what I was looking for in a company when I joined in 1983.
In May of 2015, Exton announced their West Without Borders focus on the Year of the Veteran, with The Travis Manion Foundation named as one of the recipient charities.
Come one, come all to the 2014 West without Borders campaign! From preliminary planning to the final one-ring circus, the 2014 West without Borders campaign in Kinston, N.C., was a whole lot of clowning around in the name of a good cause. This year, Kinston team members supported three charities: Relay for Life Kids’ Walk, Kid’s Cafe and Shriners’ Hospital for Children’s Transportation Fund.
For many pharmaceutical manufacturers, commercial filling lines are simply a part of the manufacturing process. But when a drug is still in development or requires prescreen stability testing for new primary container selection , small-quantity filling can be difficult. To send such quantities to a contract manufacturer or commercial lines, such as isolator or RABs, can be expensive and time consuming.
Temperature sensitive drug products, such as biologics or insulin, often require cold storage. But what, exactly is “cold”? We know it when we feel it, but often when one person is shivering, another is quite comfortable. Like humans, drug products may have specific tolerances to cold that depend upon the product.
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