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As drug development continues to evolve, further advances in delivery technologies will help to refine the overall drug delivery system, from improvements to safety and performance of delivery devices, to primary containers with consistent and higher-quality components.
Innovations in prefillable syringe plungers, such as barrier film, vision verification, particle control, steam sterilization and tighter specifications, combine designs developed to aid overall performance that will help to ensure consistency during delivery. West’s NovaPure™ plungers are the cumulative result of many of these innovations in drug protection and delivery.
For primary packaging components, West’s FluroTec™ film offers barrier protection for sensitive drug products and is an important aspect of NovaPure components, especially as we continue to see the growth of biologic drug products.
Vision verification (EnvisionTM vision inspection process ) and particle control are elements of the NovaPure component design intended to ensure customers receive the highest quality components with industry leading particle specifications.
A plunger design optimized for performance, along with steam sterilization, help to provide consistent functionality in syringe systems – an increasingly important feature especially as injection devices are used and any variability in components could impact dose delivery and injection time.
NovaPure plungers provide performance, consistency and quality to meet the needs of modern drug delivery systems. Just ask our customers.
“The 1-3mL NovaPure plunger combines West technology (4023/50, Envision, Steam) with better functionality, which is ideal for products requiring Auto-Injector delivery.”-Customer response
For more information about NovaPure components, contact us today.
NovaPure™, FluroTec™and Envision™ are trademarks of West Pharmaceutical Services, Inc. in the United States and other jurisdictions. FluroTec™ technology is licensed from Daikyo Seiko, Ltd.
The first thought that you may have when you hear the word “rubber” is natural rubber – a poly-isoprene-based polymer, which has as its origination the latex fluid drawn from rubber trees (most prominently in Indonesia and Malaysia). Although natural rubber has been used in the past for pharmaceutical applications, potential issues with latex allergies resultant from proteins from the original latex, have led to the almost complete adoption of synthetic rubber.<br />
<p>West is committed to partnering with and providing analytical and technical support for customers so that they can successfully develop drug products and deliver them to patients.</p>
Most physicians agree - of all the services that can be performed for patients, eliminating the pain and fear of injections is at the top of the list. How can pain be minimized? One approach is to maximize syringe performance - whether the syringe is employed by a clinician, in an autoinjector, or in a wearable device. A critical element of syringe performance is the break-loose force. This is the force needed to overcome the plunger inertia in a filled syringe to initiate plunger movement and introduction of drug product. A lower, more consistent, break-loose force can provide for increased patient comfort.
Daikyo Crystal Zenith® (CZ) Pre-Fillable Syringe (PFS) systems were designed to maintain purity, integrity, and efficacy of premium biopharmaceutical therapies. The system minimizes the potential contamination issues associated with glass and helps to reduce the risk of product interactions, delays in development and scale up, and possible recalls. As an extension of the existing 1mL Long Insert Needle Barrel Assembly, West and Daikyo are proud to introduce the new 2.25mL Insert Needle (IN), providing drug manufacturers a larger volume option for the next generation of autoinjectors for at-home therapies.
Last week, West once again exhibited at CPhI/Innopack—Europe’s premier trade show that brings together approximately 36,000 senior pharmaceutical professionals from more than 150 countries. West was among the show exhibitors that included providers of packaging, finished doses, machinery, ingredients, contract services, and other related services.
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