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Reducing Total Cost of Ownership
Solving the Challenge of High pH Injectable Drug ProductsClick HerePackaging Solutions for Sensitive Molecules
Solving the Challenge of Single-Use Large-Volume Delivery for Patient Self-Injection
Challenges
Reducing Total Cost of Ownership
Solving the Challenge of High pH Injectable Drug ProductsClick HerePackaging Solutions for Sensitive Molecules
Solving the Challenge of Single-Use Large-Volume Delivery for Patient Self-Injection
- Support Support
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Regulatory SupportWest Regulatory Affairs provides a single point of contact to assist with global registration strategies for all West products and processes.Letter of Authorization Form Regulatory SupportKnowledge Center
Whitepapers, bulletins, videos and seminars from the deep expertise of our teams of scientists, regulatory, and researchers.
Support
Regulatory SupportWest Regulatory Affairs provides a single point of contact to assist with global registration strategies for all West products and processes.Letter of Authorization Form Regulatory SupportKnowledge CenterWhitepapers, bulletins, videos and seminars from the deep expertise of our teams of scientists, regulatory, and researchers.
- Challenges Challenges
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Daikyo Crystal Zenith® Vials for Cell Storage at Cryogenic Temperatures
Cell therapies offer a powerful new approach to treat cancer and other serious conditions. The manufacture and supply of these therapies is complex – to address the short shelf lives of such living products, storage and shipping is done at cryogenic temperatures (liquid nitrogen, approximately -180oC). A challenge is selecting the right container system.
Glass systems cannot perform reliably at these temperatures – having the potential to fracture and lose container closure integrity. Polypropylene (PP) systems can perform well at these temperatures – but they are opaque, which prevents visual inspection. At the International Society for Cell Therapies Annual Meeting, Montreal, Dr. Alex Lyness, Manager, Research & Technology, addressed this in a poster entitled: Evaluation of a Novel Cyclic Olefin Polymer Container System for the Cryopreservation of Adherent and Suspension Human Cell Types.
The performance of container systems comprising Daikyo Crystal Zenith® cyclic olefin polymer (COP) vials was evaluated. Not only are COP vials break-resistant and completely transparent, this research demonstrated that COP vials enabled recovery of two different cell types (bone marrow and umbilical cord-derived) equal to PP systems. Further research is ongoing.
To learn more about Daikyo Crystal Zenith® packaging systems for cryogenic storage, contact your Technical Customer Service (TCS) representative, or visit the West Knowledge Center.
Crystal Zenith® is a registered trademark of Daikyo Seiko, Ltd. Crystal Zenith® technology is licensed from Daikyo Seiko, Ltd.

Daria Miller
Sr. Technical Account Specialist, TCS