Drug product delivery systems can provide comfort, ease of use and reliability—especially automated systems like West’s SmartDose® platform. This section presents papers on manual and automated delivery systems and trends in this rapidly-growing area.
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This case study can help to understand options when selecting syringe platforms to mitigate quality risks from drug development through commercialization.
<p>This article reviews the benefits of wearable delivery devices – in particular the West SmartDose® product. </p> <p><em>C. Henshall. ONDRUGDELIVERY.COM, 10-14 (2017)</em></p>
<p>This article discusses the importance of training in helping patients effectively use on-body drug delivery systems.</p> <p><em>J. Reynolds. ONdrugDelivery.com, 78, 44-46 (September 2017)</em></p>
In this article, industry experts discuss the merits of pre-filled syringes and automated delivery systems.<br /> <div> </div> <em>A. Siew. BioPharm International, 28 (8), 14-19 (2015)</em>
<p>This article discusses the issues in delivering highly viscous parenteral drug products, such as biologics.</p> <p><em>A. Fry. Pharmaceutical Technology, 38 (11) (2014)</em></p>
This article discusses the factors that affect the transport and biodistribution of drug products in the subcutaneous space, and how parenteral delivery may offer benefits versus intravenous delivery. <p><em>D.S. Collins, et al. Pharmaceutical Research (2017) (on-line, https://doi.org/10.1007/s11095-017-2229-9) </em></p>
This article discusses the benefits of pre-filled syringes based on Daikyo Crystal Zenith® cyclic olefin polymer (COP) – in terms of consistent performance and reducing the risk of interaction with drug product. <p><em>D. Stout and V. Vilavalam. Pharmaceutical Technology, Volume 2009 Supplement 6, (November 2009)</em></p>
<p>This is an excellent review of the development of pre-filled syringes, and the benefits they provide. Included is a discussion of materials of construction, including polymer-based products (e.g., with Daikyo Crystal Zenith® cyclic olefin polymer)</p> <p ><em>G. Sacha, et al. Pharmaceutical Development and Technology, 20 (1), 1-11 (2015)</em></p>
NovaPure®, FluroTec® and Ready Pack® are registered trademarks of West Pharmaceutical Services, Inc., in the United States and other jurisdictions.
SmartDose® is a registered trademark of West Pharma. Services IL, Ltd., a subsidiary of West Pharmaceutical Services, Inc.
West markets SmartDose® as a multi-component system only. Final assembly of the prefilled component is completed by the pharmaceutical company.
Daikyo Crystal Zenith® is a registered trademark of Daikyo Seiko, Ltd.
Daikyo Crystal Zenith® technology is a registered trademark of Daikyo Seiko, Ltd.