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By Amy Miller & Jennifer Riter

April 09, 2012

Dr. Heike Kofler, Amy Miller, Jennifer Riter
West Pharmaceutical Services, Inc.

One of the critical success factors for packaging lyophilized drugs is protection against product degradation caused by moisture. Moisture can be introduced into a lyophilized drug product cake from the elastomeric stopper and from the atmospheric headspace; it can also permeate through the stopper, a process known as moisture transmission.