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Scientific Insights Help Ensure High-Quality Outcomes
At West, our goal is to partner with customers to mitigate risks of drug/packaging incompatibility, container/device and functional challenges. Although we consider critical quality attributes during development of drug packaging and delivery systems, there can be knowledge gaps of various interfaces based on the specific application of use, such as component-to-container, container-to-device, and container-to-drug.
Formed in 2016, Scientific Insights Lab brings together experts with broad knowledge and experience in polymer materials, surface science, biologic drugs and computational modeling. We help customers understand, select, optimize and improve container closure system targeting specific to their drug product applications and manufacturing process.
Our comprehensive protein testing capabilities include:
system screening
protein adsorption analysis
biologic activities assay
primary structure analysis
protein particles & aggregation testing
protein thermal stability
product-related structure & impurities
We also perform surface analytical and functionality testing capabilities to assess drug impacts on containers over time. Using theoretical prediction and experimental verification, we assist our customers to predict long term container/drug compatibility at the early stage of combination product development.
Finally, we can perform container closure system (CCS) compatibility and optimization testing for high-quality performance. When used in combination with the comprehensive container closure integrity (CCI) testing methods, our experts can serve customers with
CCS analysis
components selection/recommendation
process set up, troubleshooting & optimization.
By partnering together, West’s experts offer customers the ability to understand the interactions of containers and their new drug products, to provide solutions of container closure systems to mitigate risks down the road in a close, collaborative customer relationship.
Learn more by watching our video above or visiting our featured video channel for additional videos!
Beyond the challenges of ensuring that data privacy laws are observed across the globe, West IT is faced with the need to safeguard intellectual property, trade secrets, and confidential company and employee data while ensuring that we can serve our global customers. This is becoming increasingly more complex with the rapid advances in mobility and cloud computing. At West, IT is evaluating the best way to enable our employees to take advantage of these rapid advances in technology while still ensuring protection for confidential company information.
<p><span class="Subheading-1">Daikyo Crystal Zenith<sup>®</sup> container systems may be your solution!</span></p><p><span>Bisphosphonates are a class of drugs used to help prevent loss of bone density in diseases such as osteoporosis. This class inhibits increased loss of calcium from bones (bone resorption) by promoting apoptosis (elimination of cells absent release of harmful substances into surrounding area) of osteoclasts. Osteoclasts function to break down bone to assist with bone maintenance and to help balance blood calcium levels; however, in the case of patients with osteoporosis, there is an increased level of bone resorption that results in a need to manage and decrease the presence of the osteoclasts.</span></p>
Recently, interns of West’s global headquarters in Exton, Pennsylvania, hosted a Final Showcase Event where they highlighted various elements of their overall internship experience. The showcase, which included each intern creating a poster to highlight and present their experience, served as a final opportunity for the interns to continue to network with other members of the West team as they finished the ninth week of the ten-week West Ambassador Internship Program.
West will be exhibiting at the Partnership Opportunities in Drug Delivery (PODD) Conference on October 14-15, 2014 at the Renaissance Boston Waterfront Hotel. West’s Zach Marks will be presenting an overview of the SmartDose® electronic wearable injector.